Washington, Jan 31: How long does a person live? Researchers from the University of Edinburgh say that the answer to this question lies in their DNA. A group of scientists have identified that a biological clock in human DNA can tell a person’s longevity. Read: Revealed — 5 simple steps to live a healthy, long life)

DNA methylation – How is it related to longevity?

The researchers at University of Edinburgh studied DNA methylation, a chemical modification of DNA (that takes place during the process of DND replication). This process occurs over a person’s lifetime and can help to predict an individual’s age when an individuals’ actual age is compared with their predicted biological clock age. The scientists   observed a pattern emerging on doing this process.

Although this modification does not change the DNA sequence, it plays a key role in the biological processes and also influences the genes activation and inhibition. The DNA methylation changes can affect many genes and it occurs throughout a person’s life. (Read:Molecules targeting biological clock of cells hold potential for cancer treatment)

How were the results interpreted?

The results stated that people whose biological age was greater than their true age were more likely to die sooner than those whose biological and actual ages were the same. Even after accounting for other factors such as smoking, diabetes and cardiovascular disease, researchers found that the link between having a faster-running biological clock and early death held true.

Earlier studies vs the current study

Riccardo Marioni, a researcher said that the same results in four studies indicated a link between the biological clock and deaths from all the above listed causes. However, at present, it is not very clear about what factors (lifestyle or genetic) influence a person’s biological age. They have several follow-up study projects that are planned to investigate this matter in detail. (Read: It’s official – happy people live healthier, for longer!)

Researcher Ian Deary said, ‘This research increases our understanding of longevity and healthy ageing, which is very exciting as it has identified a novel indicator of ageing. This study improves the prediction of lifespan over and above many contributory factors such as smoking, diabetes and cardiovascular disease.’

With inputs from ANI

Image Source: Getty Images

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